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本书是国家自然科学基金项目资助项目，采用激光微纳制造技术制造人工骨。目前常用的人造骨只能起到功能替代的作用，无法实现受损后自我修复，主要是因为人工骨成型过程中无法实现其微纳结构的控制，从而难以实现成骨分化的诱导作用。本书在国家自然科学基金5项等项目的支持下，开展降解可控的多孔人工骨支架结构设计和精细制造及与之对应的诱导成骨的机理研究，构建了具有自我修复功能的纳米晶粒陶瓷人工骨的激光微纳制造理论与方法。
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Chapter?1Laser?sintering?system
Development?of?a?novel?laser-sintering?machine?for?fabrication?of?artificial?bone
Structural?analysis?and?design?optimization?of?a?selective?laser?sintering?system
Control?software?development?of?a?novel?rapid?prototype?laser?sintering?system?for?fabricating?artificial?bone
Realization?of?NURBS?forcranium?in?a?laser?sintering?machine
Simulation?of?temperature?field?during?the?laser?sintering?process?of?nano-hydroxyapatite?powder
Chapter?2Laser?sintering?process?experiments
Microstructure,?mechanical?properties?and?in?vitro?bioactivity?of?akermanite?scaffolds?fabricated?by?laser?sintering
Microstructure?evolution?and?mechanical?properties?improvement?in?liquid-phase-sintered?hydroxyapatite?by?laser?sintering
Laser?sintering?of?nano?13-93?glass?scaffolds:?microstructure,?mechanical?properties?and?bioactivity
Improvement?of?mechanical?properties?by?the?addition?of?akermauite?and?45S5?bioglass?in?13-tricalcium?phosphate
Akermanite?scaffolds?reinforced?with?boron?nitride?nanosheets?in?bone?tissue?engineering
Chapter?3Micro-nano?structure?of?artificial?bone
A?novel?two-step?sintering?for?nano-hydroxyapatite?scaffolds?for?bone?tissue?engineering
Preparation?of?micronanometer-sized?porous?surface?structure?of?calcium?phosphate?scaffolds?and?the?influence?on?biocompatibility
Graphene?oxide?reinforced?poly?vinyl?alcohol?:?nanocomposite?scaffolds?for?tissue?engineering?applications
Silicon?carbide?whiskers?reinforced?akermanite?scaffolds?for?tissue?engineering
Effect?of?nano-zirconia?on?the?mechanical?and?biological?properties?of?calcium?silicate?scaffolds
Chapter?4Mechanical?properties?of?artificial?bone
Liquid?phase?sintered?ceramic?bone?scaffolds?by?combined?laser?and?furnace
Mechanisms?of?tetraneedlelike?ZnO?whiskers?reinforced?forsteritebioglass?scaffolds
Mechanical?reinforcement?of?diopside?bone?scaffolds?with?carbon?nanotnbes
A?bioactive?glass?nanocomposite?scaffold?tougbed?by?multi-wall?carbon?nanotubes?for?tissue?engineering
Toughening?and?strengthening?mechanisms?of?porous?akermanite?scaffolds?reinforced?with?nano-titania
Chapter?5Biological?properties?of?artificial?bone
Nano?SiO2?and?MgO?improve?the?properties?of?porous?B-TCP?scaffolds?via?advanced?manufacturing?technology
Calcium?silicate?ceramic?scaffolds?toughened?with?hydroxyapatite?whiskers?for?bone?tissue?engineering
Bioactivity?improvement?of?forsterite-based?scaffolds?with?nano-58S?bioactive?glass
Hydroxyapatite?whisker?reinforced?63s?glass?scaffolds?for?bone?tissue?engineering
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