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內容簡介: |
Oneoftheleadingcancerresearchersintheworld,RobertA.Weinbergisperfectlysuitedtodescribethesearchforcancer''soriginsfromtheearlydaysofthiscenturytothepresent.Presuminglittleknowledgeofbiology,hetellshowacancer-causingviruswasfirstdiscoveredin1909,howthecorrelationwasmadebetweenchemicalcarcinogensandcancer,andhowoncogenesthegenesthatcanturnacellmalignantwork.Heexplainsclearlyhowmalignantcellssendmessagestooneanotherandalsoblockthemessagesofnormalcells.Finally,Weinbergpredictsthatcancerpreventionmaydependonourabilitytounderstandthemysteriouschemicalclockthatregulatesourcells''mostbasicfunctions.OneRenegadeCelloffersaconcise,accessiblerouteintothecomplexandoftendauntingworldofcancerandcancerresearch.
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關於作者: |
AFoundingMemberofWhiteheadInstitute,RobertA.Weinberg?isapioneerincancerresearchmostwidelyknownforhisdiscoveriesofthefirsthumanoncogene—agenethatcausesnormalcellstoformtumors—andthefirsttumorsuppressorgene.Weinberg,whoreceivedhisPhDinbiologyfromtheMassachusettsInstituteofTechnologyin1969,hasheldresearchpositionsattheWeizmannInstituteandtheSalkInstitute.In1982,WeinberghelpedfoundWhiteheadInstitute,joinedthefacultyasaprofessorofbiologyatMIT,andpublishedhislandmarkpaper"MechanismofActivationofaHumanOncogene"inthejournalNature.In1999,anothermajorpaper,"CreationofHumanTumorCellswithDefinedGeneticElements,"wasalsopublishedinNature.
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